Department of Molecular Biology & Genetics

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News

Feb 15

Andrew Holland, Ph.D. receives President’s Frontier Award

Dec 31

Josh Modell, Ph.D., awarded 2020 Johns Hopkins Discovery Award

Dec 16

Carol Greider, Ph.D. elected to National Academy of Inventors

Aug 06

Welcome Jeff Coller, Ph.D.

Aug 06

How Cells Learn to “Count” – Andrew Holland, Ph.D.

Jul 07

Geraldine Seydoux, Ph.D elected as EMBO Associate Member

Jan 27

Jeremy Nathans, M.D., Ph.D, is the 2020 recipient of the Benjamin Franklin Medal in Life Science

Recent Publications

Workman RE, Pammi T, Nguyen BTK, Graeff LW, Smith E, Sebald SM, Stoltzfus MJ, Euler CW, Modell JW. (2021) A natural single guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression. Cell. 2021 Jan 6:S0092-8674(20)31687-1. doi: 10.1016/j.cell.2020.12.017. Epub ahead of print. PMID: 33421369. [link] [pdf]

Pokrass MJ, Ryan KA, Xin T, Pielstick B, Timp W, Greco V, Regot S. Cell Cycle Dependent ERK Signaling Dynamics Directs Fate Specification in the Mammalian Preimplantation Embryo. (2020) Developmental Cell. [link] [pdf]

Aikin T, Peterson A, Pokrass MJ, Clark HR, Regot S. MAPK Activity Dynamics Regulates Non-Cell Autonomous Effects of Oncogene Expression. (2020) Elife. Sep 17;9:e60541. [link] [pdf]

Rattner A, Terrillion CE, Jou C, Kleven T, Hu SF, Williams J, Hou Z, Aggarwal M, Mori S, Shin G, Goff LA, Witter MP, Pletnikov M, Fenton AA, Nathans J. (2020) Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Elife. 9:e62766. doi: 10.7554/eLife.62766. PMID: 33084572 [link]

Pinkard O, McFarland S, Sweet T, Coller J. Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation. Nature Communications. 2020;11(1):4104. Published 2020 Aug 14. doi:10.1038/s41467-020-17879-x [link]

Schaffer, AE, Pinkard, O., and Coller J (2019). tRNA Metabolism and Neurodevelopmental Disorders. Annual Reviews Genomics Human Genetics. PMID 31082281. [ link ] [ pdf ]

Chang TH, Hsieh FL, Smallwood PM, Gabelli SB, Nathans J. (2020) Structure of the RECK CC domain, an evolutionary anomaly. Proceedings of the National Academy of Sciences of the United States of America.117(26):15104-15111. doi: 10.1073/pnas.2006332117. Epub 2020 Jun 15. PMID: 32541044 [link]