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Jin P, Duan R, Luo F, Zhang G, Hong N, Chen EH. (2011) Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Developmental Cell 20:623-638. [ link ]

Zhang L, Reynolds TL, Shan X, Desiderio S. (2011) Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis. Immunity 34: 163-174. [ link ]

Regot S, Macia J, Conde N, Furukawa K, Kjellén J, Peeters T, Hohmann S, de Nadal E, Posas F, Solé R. (2011) Distributed biological computation with multicellular engineered networks. Nature 469(7329):207-11. doi: 10.1038/nature09679. [ link ]

Chen EH. (2011) Invasive podosomes and myoblast fusion. Membrane Fusion (Elsevier, USA), pp. 235-258. [ link ]

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Sens KL, Zhang S, Jin P, Duan R, Zhang G, Luo F, Parachini L, Chen EH. (2010) An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. Journal of Cell Biology 191, 1013-1027. [ link ]

Cai J, Zhang N, Zheng Y, de Wilde RF, Maitra A, and Pan D. (2010) The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes & Devopment, (24): 2383-2388. [ pdf ]

Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders AA, and Pan D.(2010) The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. Devopmental Cell, (19): 27-38. [ pdf ]

Yu J, Zheng Y, Dong J, Klusza S, Deng W-M, and Pan D. (2010) Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Developmental Cell, 18: 288-99. [ pdf ]

Greider, C.W. (2010) Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle (Nobel Lecture). Angew. Chem. Int. Ed. Engl. 49:7422-7439. [ pdf ]

Kim Y*, Holland AJ*, Lan W, Cleveland DW. (2010). Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E. Cell. 142, 444-455. [ link ]

Corden JL. (2010). Shining a new light on RNA-protein interactions. Chemistry & Biology. 17(4):316-318. [ link ]

Holland AJ, Lan W, Niessen S, Hoover H, Cleveland DW. (2010). Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. Journal of Cell Biology. 188, 191-198. [ link ]

Vidal-Cardenas SL, Greider CW. (2010). Comparing effects of mTR and mTERT deletion on gene express and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase. Nucleic Acids Research. 38: 60-71. [ link ]

Armanios M, Alder JK, Parry EM, Karim B, Strong MA, Greider CW. (2009). Short telomeres are sufficient to cause the degenerative defects associated with aging. American Journal of Human Genetics. 85, 823-832. [ link ]

Urban S. (2009) Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms. Nature Reviews Microbiology 7, 411–423. [ link ]

Corden JL. (2008). Yeast Pol II start-site selection: the long and the short of it. EMBO Reports. 9:1084-1086. [ link ]

Wu S, Liu Y, Zheng Y, Dong J and Pan D. (2008) The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Developmental Cell, 14, 388-98. [ pdf ]

Baxt LA, Baker RP, Singh U, Urban S. (2008) An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion. Genes & Development 22, 1636–1646. [ link ]

Zhang S, Chen EH. (2008). Ultrastructural analysis of myoblast fusion in Drosophila. Methods in Molecular Biology. 475, 275–297. [ link ]

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Dong J, Feldman G, Huang J, Wu S, Zhang N, Comerford S A, Gayyed M F, Anders R A, Maitra A, and Pan, D. (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals Cell 130, 1120-1133. [ pdf ]

Dong J, Feldman G, Huang J, Wu S, Zhang N, Comerford S A, Gayyed M F, Anders R A, Maitra A, and Pan D. (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell (130), 1120-1133. [ pdf ]

Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S. (2007). A plant homeodomain in RAG-2 that binds hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement. Immunity. 27:561-71. [ link ]

Baker RP, Young K, Feng L, Shi Y, Urban S. (2007) Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate. Proceedings of the National Academy of Sciences USA 104, 8257–8262. [ link ]

Kaur R, Ma B, Cormack BP. (2007). A family of glycosylphosphatidylinositol-linked asparyl proteases is required for virulence of Candida glabrata. Proceedings of the National Academy of Sciences USA. 104:7628-7633. [ link ]

Feldser D, Greider CW. (2007). Short telomeres limit tumor progression in vivo by inducing senescence. Cancer Cell. 11, 461-469. [ link ]

Kim S, Shilagardi K, Zhang S, Hong S, Sens K, Bo J, Gonzalez GA, Chen EH. (2007). A Critical Function for the Actin Cytoskeleton in Targeted Exocytosis of Prefusion Vesicles during Myoblast Fusion. Developmental Cell. 12, 571-86. [ link ]

Baker RP, Wijetilaka R, Urban S. (2006) Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria. PLoS Pathogens 2, e113. [ link ]

Caraveo G, van Rossum DB, Patterson RL, Snyder SH, Desiderio S. (2006). Action of TFII-I outside the nucleus as an inhibitor of agonist-induced calcium entry. Science. 314:122-5. [ link ]

Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW. (2005). Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity. Cell. 123: 1121-1131. [ link ]

Huang J, Wu S, Barrera J, Matthews K, and Pan, D.(2005) The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homologue of YAP. Cell 122, 421-434. [ pdf ]

Chen EH, Olson EN. (2005). Unveiling the mechanisms of cell-cell fusion. Science 308, 369-373. [ link ]

Brossier F, Jewett TJ, Sibley LD, Urban S. (2005) A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma. Proceedings of the National Academy of Sciences USA 102, 4146–4151. [ link ]

Urban S, Wolfe MS. (2005) Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity. Proceedings of the National Academy of Sciences USA 102, 1883–1888. [ link ]

Castaño I, Pan S, Zupancic M, Hennequin C, Dujon B, Cormack BP. (2005). Telomere length control and transcriptional regulation of sub-telomeric adhesins in Candida glabrata. Molecular Microbiology. 55: 1246-1258. [ link ]

Domergue R, Castaño I, De Las Peñas A, Zupancic M, Lockatell V, Hebel JR, Johnson D, Cormack BP. (2005). Nicotinic acid limitation regulates silencing of Candida adhesins during UTI. Science. 308: 866-870 [ link ]

Frieman MB, Cormack BP. (2003). The omega-site sequence of glycosylphosphatidylinositol-anchored proteins in Saccharomyces cerevisiae can determine distribution between the membrane and the cell wall. Molecular Microbiology. 50: 883-896. [ link ]

Wu S, Huang J, Dong J, Pan, D. (2003) hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell (114), 445-456. [ pdf ]

Urban S, Freeman M. (2003) Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Molecular Cell 11, 1425–1434. [ link ]

IJpma A, Greider CW. (2003). Short telomeres induce a DNA damage response in S. cerevisiae. Molecular Biology of the Cell. 14: 987-1001. [ link ]

Urban S, Lee JR, Freeman M. (2002) A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO Journal 21, 4277–4286. [ link ]

Urban S, Lee JR, Freeman M. (2001) Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases. Cell 107, 173–182. [ link ]

Hemann, M.T., Strong, M., Hao, L.-Y., and Greider, C.W. (2001) The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 107: 66-77. [ pdf ]

Chen, J.-L., Blasco, M, and Greider, C.W. (2000) A Secondary structure of vertebrate telomerase RNA. Cell 100:503-514. [ pdf ]